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产品信息
H00011041-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2H6
抗原
B4GAT1 (NP_006867.1, 316 a.a. approximately 415 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: AYVVPWQDPW EPFYVAGGKV PTFDERFRQY GFNRISQACE LHVAGFDFEV LNEGFLVHKG FKEALKFHPQ KEAENQHNKI LYRQFKQELK AKYPNSPRRC
靶标信息
Beta-1,4-glucuronyltransferase involved in O- mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O- mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha- dystroglycan (DAG1).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B3GNT1 (HGNC:15685); beta-1,3-N-acetylglucosaminyltransferase bGnT-6; Beta-1,4-glucuronyltransferase 1; EC 2.4.1.149; I-beta-1,3-N-acetylglucosaminyltransferase; iGnT; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
基因别名: B3GN-T1; B3GNT1; B3GNT6; B4GAT1; BETA3GNTI; iGAT; iGNT; MDDGA13
UniProt ID: (Human) O43505
Entrez Gene ID: (Human) 11041
