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产品信息
PA5-96744
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 309-418 of human BAAT (NP_0016921)
偶联物
形式
Liquid
浓度
2.36 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808546
产品详细信息
Immunogen sequence: YLFPIEEAQG QFLFIVGEGD KTINSKAHAE QAIGQLKRHG KNNWTLLSYP GAGHLIEPPY SPLCCASTTH DLRLHWGGEV IPHAAAQEHA WKEIQRFLRK HLIPDVTSQL; Positive Samples: Jurkat, BT-474, A-549, HepG2, Mouse liver, Rat liver; Cellular Location: Cytoplasm
靶标信息
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BACAT; BAT; bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase); bile acid CoA:amino acid N-acyltransferase; bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase); Bile acid-CoA thioesterase; Bile acid-CoA:amino acid N-acyltransferase; bile acid-Coenzyme A dehydrogenase: amino acid n-acyltransferase; bile acid-Coenzyme A: amino acid N-acyltransferase; Choloyl-CoA hydrolase; Glycine N-choloyltransferase; Kan-1; Long-chain fatty-acyl-CoA hydrolase; taurine N-acyltransferase
基因别名: AI118337; AI158864; BAAT; BACAT; BAT; kan-1
UniProt ID: (Human) Q96L31, (Mouse) Q91X34, (Rat) Q63276
Entrez Gene ID: (Human) 570, (Mouse) 12012, (Rat) 29725
receptor binding
protein binding
palmitoyl-CoA hydrolase activity
N-acyltransferase activity
transferase activity, transferring acyl groups
glycine N-choloyltransferase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
transferase activity
hydrolase activity
thiolester hydrolase activity
molecular_function
esterase
hydrolase
metabolite interconversion enzyme
