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BAG1 Antibody (PA5-78851) in IHC (P)
Immunohistochemistry analysis of BAG1 on paraffin-embedded rat intestine tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with BAG1 polyclonal antibody (Product# PA5-78851) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). Developm... View More
产品信息
PA5-78851
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human Bag1 (323-345aa DTVEQNICQETERLQSTNFALAE).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2745967
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
基因别名: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
negative regulation of protein phosphorylation
apoptotic process
neuron differentiation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
chaperone cofactor-dependent protein refolding
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
response to lithium ion
response to organic cyclic compound
response to nicotine
response to drug
cell surface receptor signaling pathway
regulation of catalytic activity
regulation of cellular response to heat
