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Immunogen sequence: LITQLAKELS NKGVLKTQAE NTNKAAKKFM EENEKLKRIL KSHGKDEECV LEAE
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.
Bap29 and the related protein Bap31 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Both Bap29 and Bap31 interact with membrane-bound immunoglobulins (mIgs), such as IgM and IgD, which with Ig-alpha/Ig-beta heterodimers form B cell antigen receptors. Binding of the Bap29/Bap31 heterodimer correlates with the ER retention of non-Ig-alpha/Ig-beta bound mIg complexes, suggesting that Bap29 and Bap31 may act as chaperones transmembrane regions of various proteins. Bap29 possesses multiple isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B-cell receptor-associated protein 29; BCR-associated protein 29
基因别名: BAP29; BCAP29
UniProt ID: (Human) Q9UHQ4
Entrez Gene ID: (Human) 55973