Abnova

BBS4 Polyclonal Antibody, MaxPab™

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抗体检测数据 (1)

BBS4 Antibody in Western Blot (WB)

BBS4 Antibody in Western Blot (WB)

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BBS4 Antibody (H00000585-B01P) in WB

Western Blot analysis of BBS4 expression in transfected 293T cell line by BBS4 MaxPab polyclonal antibody. Lane 1: BBS4 transfected lysate(57.09 KDa). Lane 2: Non-transfected lysate. .

BBS4 Antibody in Western Blot (WB)

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BBS4 Antibody in Western Blot (WB) — Western Blot analysis of BBS4 expression in transfected 293T cell line by BBS4 MaxPab polyclonal antibody. Lane 1: BBS4 transfected lysate(57.09 KDa). Lane 2: Non-transfected lysate. .

产品信息

H00000585-B01P

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG

分类

Polyclonal

类型

Antibody

抗原

BBS4 (NP_149017.2, 1 a.a. approximately 519 a.a) full-length human protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MAEERVATRT QFPVSTESQK PRQKKAPEFP ILEKQNWLIH LHYIRKDYEA CKAVIKEQLQ ETQGLCEYAI YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA IEVYNEAAKL NQKDWEISHN LGVCYIYLKQ FNKAQDQLHN ALNLNRHDLT YIMLGKIHLL EGDLDKAIEV YKKAVEFSPE NTELLTTLGL LYLQLGIYQK AFEHLGNALT YDPTNYKAIL AAGSMMQTHG DFDVALTKYR VVACAVPESP PLWNNIGMCF FGKKKYVAAI SCLKRANYLA PFDWKILYNL GLVHLTMQQY ASAFHFLSAA INFQPKMGEL YMLLAVALTN LEDIENAKRA YAEAVHLDKC NPLVNLNYAV LLYNQGEKKN ALAQYQEMEK KVSLLKDNSS LEFDSEMVEM AQKLGAALQV GEALVWTKPV KDPKSKHQTT STSKPASFQQ PLGSNQALGQ AMSSAAAYRT LPSGAGGTSQ FTKPPSLPLE PEPAVESSPT ETSEQIREK

靶标信息

BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Bardet-Biedl syndrome 4 protein; BBSome complex member BBS4

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基因别名: BBS4

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UniProt ID: (Human) Q96RK4

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Entrez Gene ID: (Human) 585

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RNA polymerase II repressing transcription factor binding microtubule motor activity protein binding dynactin binding alpha-tubulin binding beta-tubulin binding

microtubule cytoskeleton organization mitotic cytokinesis neuron migration neural tube closure retina homeostasis heart looping negative regulation of systemic arterial blood pressure spermatid development visual perception sensory perception of smell negative regulation of gene expression protein transport dendrite development regulation of lipid metabolic process ventricular system development striatum development hippocampus development cerebral cortex development adult behavior negative regulation of actin filament polymerization melanosome transport regulation of cytokinesis protein localization to organelle negative regulation of GTPase activity microtubule anchoring at centrosome nonmotile primary cilium assembly social behavior photoreceptor cell outer segment organization negative regulation of appetite by leptin-mediated signaling pathway positive regulation of multicellular organism growth cilium assembly fat cell differentiation photoreceptor cell maintenance positive regulation of cilium assembly retinal rod cell development intracellular transport brain morphogenesis sensory processing centrosome organization maintenance of protein location in nucleus regulation of stress fiber assembly cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility face development fat pad development protein localization to cilium protein localization to centrosome regulation of nonmotile primary cilium assembly protein localization to photoreceptor outer segment