Invitrogen

BBS4 Polyclonal Antibody

查看其他10个BBS4抗体

抗体检测数据 (3)

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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BBS4 Antibody (PA5-104328) in IHC (P)

Immunohistochemistry analysis of BBS4 in mouse kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with BBS4 polyclonal antibody (Product # PA5-104328) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.

BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

BBS4 Antibody in Western Blot (WB)

BBS4 Antibody in Western Blot (WB)

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BBS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of BBS4 in mouse kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with BBS4 polyclonal antibody (Product # PA5-104328) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.

BBS4 Antibody in Western Blot (WB) — Western blot analysis of BBS4 in mouse brain (Lane 1: treated with blocking peptide). Samples were incubated with BBS4 polyclonal antibody (Product # PA5-104328).

BBS4 Antibody in Western Blot (WB) — Western blot analysis of BBS4 in HeLa cells. Samples were incubated with BBS4 polyclonal antibody (Product # PA5-104328).

产品信息

PA5-104328

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

-

免疫组化（石蜡） (IHC (P))

1:50-1:200

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human BBS4(Accession Q96RK4), corresponding to amino acid residues K220-P270.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2853638

产品详细信息

Antibody detects endogenous levels of total BBS4.

靶标信息

BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Bardet-Biedl syndrome 4 homolog; Bardet-Biedl syndrome 4 protein; Bardet-Biedl syndrome 4 protein homolog; BBSome complex member BBS4

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基因别名: AW537059; AW742241; BBS4; D9Ertd464e

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UniProt ID: (Human) Q96RK4, (Mouse) Q5EBJ7

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Entrez Gene ID: (Human) 585, (Mouse) 102774, (Rat) 300754

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RNA polymerase II repressing transcription factor binding microtubule motor activity protein binding dynactin binding alpha-tubulin binding beta-tubulin binding molecular_function

microtubule cytoskeleton organization mitotic cytokinesis neural tube closure retina homeostasis negative regulation of systemic arterial blood pressure transport spermatid development sensory perception of smell protein localization metabolic process negative regulation of gene expression protein transport dendrite development regulation of lipid metabolic process ventricular system development striatum development hippocampus development cerebral cortex development cell projection organization adult behavior negative regulation of actin filament polymerization regulation of cytokinesis leptin-mediated signaling pathway protein localization to organelle negative regulation of GTPase activity microtubule anchoring at centrosome nonmotile primary cilium assembly social behavior photoreceptor cell outer segment organization negative regulation of appetite by leptin-mediated signaling pathway positive regulation of multicellular organism growth cilium assembly response to leptin photoreceptor cell maintenance positive regulation of cilium assembly retinal rod cell development brain morphogenesis centrosome organization maintenance of protein location in nucleus regulation of stress fiber assembly cilium morphogenesis regulation of cilium beat frequency involved in ciliary motility face development fat pad development protein localization to cilium protein localization to centrosome regulation of nonmotile primary cilium assembly protein localization to photoreceptor outer segment neuron migration heart looping visual perception melanosome transport fat cell differentiation intracellular transport sensory processing biological_process