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BCAS3 Antibody (PA5-80373) in ICC/IF
Immunofluorescence staining of BCAS3 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with BCAS3 Polyclonal Antibody (Product # PA5-80373, 1:1,000) at 4°C overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm and nucleus.
产品信息
PA5-80373
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the center region of the Human BCAS3
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787697
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human BCAS3.
靶标信息
BCAS3 is physically associated with histone H3 and histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor) and possesses histone acetyltransferase activity. In breast cancer, several chromosomal sites frequently undergo amplification, implicating the location of genes important for tumor development and progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCAS3 microtubule associated cell migration factor; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 3; breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 3; GAOB1; Maab1 protein; metastasis associated antigen of breast cancer; protein Maab1; Rudhira
基因别名: BCAS3; GAOB1; MAAB
UniProt ID: (Human) Q9H6U6
Entrez Gene ID: (Human) 54828
angiogenesis
transcription, DNA-templated
Golgi organization
positive regulation of endothelial cell migration
vesicle-mediated transport
microtubule organizing center organization
negative regulation of GTPase activity
tube formation
response to starvation
positive regulation of catalytic activity
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of filopodium assembly
negative regulation of focal adhesion assembly
cellular response to estrogen stimulus
positive regulation of intracellular protein transport
activation of GTPase activity
regulation of establishment of cell polarity
positive regulation of actin cytoskeleton reorganization
