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产品信息
PA5-96622
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_0601493)
偶联物
形式
Liquid
浓度
0.54 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808424
产品详细信息
Immunogen sequence: LAGLVPPGSP GPITRHGSYD SLASDHSGQE DEEWLSQVEI VTHTGPHRRL WMGPQFQFKT IHPSGQTTVI SSSSSVLQSH GPSDTPQPLL DFDTDDLDLN SLRIQPVRSD PVSMPGSSRP VSDRRGVSTV IDAASGTFDR SVTLLEVCGS WPEGFGLRHM SSMEHTEEGL RERLADAMAE SPSRDVVGSG TELQREGSIE TLSNSSGSTS GSIPRNFDGY RSPLPTNESQ PLSLFPTGFP; Positive Samples: HeLa, BT474, Rat brain; Cellular Location: Cytoplasm, Nucleus, cytoskeleton
靶标信息
BCAS3 is physically associated with histone H3 and histone acetyltransferase complex protein P/CAF (p300/CBP-associated factor) and possesses histone acetyltransferase activity. In breast cancer, several chromosomal sites frequently undergo amplification, implicating the location of genes important for tumor development and progression.
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生物信息学
蛋白别名: BCAS3 microtubule associated cell migration factor; BCAS4/BCAS3 fusion; breast carcinoma amplified sequence 3; breast carcinoma amplified sequence 4/3 fusion protein; Breast carcinoma-amplified sequence 3; Breast carcinoma-amplified sequence 3 homolog; GAOB1; K20D4; Maab1 protein; metastasis associated antigen of breast cancer; protein Maab1; Protein rudhira; Rudhira
基因别名: 1500019F07Rik; 2610028P08Rik; AU021018; BC028339; BCAS3; GAOB1; K20D4; MAAB; RGD1560788; rudhira
UniProt ID: (Human) Q9H6U6, (Mouse) Q8CCN5
Entrez Gene ID: (Human) 54828, (Mouse) 192197, (Rat) 363662
angiogenesis
transcription, DNA-templated
Golgi organization
positive regulation of endothelial cell migration
vesicle-mediated transport
microtubule organizing center organization
negative regulation of GTPase activity
tube formation
response to starvation
positive regulation of catalytic activity
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
positive regulation of filopodium assembly
negative regulation of focal adhesion assembly
cellular response to estrogen stimulus
positive regulation of intracellular protein transport
activation of GTPase activity
regulation of establishment of cell polarity
positive regulation of actin cytoskeleton reorganization
regulation of transcription, DNA-templated
biological_process
