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产品信息
PA5-120441
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2).
偶联物
形式
Liquid
浓度
1.29 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914013
产品详细信息
Positive test controls include: Jurkat, Raji, SH-SY5Y, Neuro-2a, Mouse brain. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: EVVGTFKAKD LIVTPATILK EKPDPNNLVF GTVFTDHMLT VEWSSEFGWE KPHIKPLQNL SLHPGSSALH YAVELFEGLK AFRGVDNKIR LFQPNLNMDR MYRSAVRATL PVFDKEELLE CIQQLVKLDQ EWVPYSTSAS LYIRPTFIGT EPSLGVKKPT KALLFVLLSP V
靶标信息
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCAT(c); branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; placental protein 18; Protein ECA39
基因别名: BCAT1; BCATC; BCT1; ECA39; MECA39; PNAS121; PP18
UniProt ID: (Human) P54687, (Mouse) P24288, (Rat) P54690
Entrez Gene ID: (Human) 586, (Mouse) 12035, (Rat) 29592
branched-chain-amino-acid transaminase activity
pyridoxal phosphate binding
identical protein binding
L-leucine transaminase activity
L-valine transaminase activity
L-isoleucine transaminase activity
catalytic activity
transaminase activity
transferase activity
transaminase
transferase
metabolite interconversion enzyme
G1/S transition of mitotic cell cycle
aspartate biosynthetic process
cell proliferation
branched-chain amino acid biosynthetic process
branched-chain amino acid catabolic process
leucine biosynthetic process
valine biosynthetic process
metabolic process
cellular amino acid biosynthetic process
branched-chain amino acid metabolic process
mitotic G1 DNA damage checkpoint
cellular response to UV
biological_process
