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BCL11B Antibody (MA5-32546) in ICC/IF
Immunofluorescence analysis of BCL11B was performed using 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with BCL11B Recombinant Rabbit Monoclonal Antibody (JF09-90) (Product # MA5-32546) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Recombinant Secondary Antibo... View More
产品信息
MA5-32546
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JF09-90
抗原
Synthetic peptide within Human Ctip2 aa 491-534
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2809823
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell CLL/lymphoma 11B; B-cell CLL/lymphoma 11B (zinc finger protein); B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein; B-cell lymphoma/leukaemia 11B; B-cell lymphoma/leukemia 11B; BCL-11B; BCL11B/TRDC fusion; COUP-TF-interacting protein 2; hRit1; Radiation-induced tumor suppressor gene 1 protein; zinc f; zinc finger protein hRit1 alpha
基因别名: ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; BCL11B; CTIP-2; CTIP2; hRIT1-alpha; RIT1; ZNF856B
UniProt ID: (Human) Q9C0K0
Entrez Gene ID: (Human) 64919
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
DNA-binding transcription factor
zinc finger transcription factor
C2H2 zinc finger transcription factor
gene-specific transcriptional regulator
keratinocyte development
epithelial cell morphogenesis
transcription from RNA polymerase II promoter
signal transduction
negative regulation of cell proliferation
regulation of keratinocyte proliferation
regulation of lipid metabolic process
striatal medium spiny neuron differentiation
commitment of neuronal cell to specific neuron type in forebrain
neurogenesis
post-embryonic camera-type eye development
T cell differentiation in thymus
T cell receptor V(D)J recombination
odontogenesis of dentin-containing tooth
negative regulation of apoptotic process
positive T cell selection
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
alpha-beta T cell differentiation
thymus development
olfactory bulb axon guidance
