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产品信息
PA5-76568
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein of human Bcl9
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720295
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
BCL9 is involved in signal transduction through the Wnt pathway. It promotes beta-catenin's transcriptional activity. BCL9 is associated with B-cell acute lymphoblastic leukemia. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; bcl-9; nuclear co-factor of beta-catenin signalling; Protein legless homolog
基因别名: 2610202E01Rik; 8030475K17Rik; A330041G23Rik; BCL9; Gm130; LGS
UniProt ID: (Human) O00512, (Mouse) Q9D219
Entrez Gene ID: (Human) 607, (Mouse) 77578, (Rat) 310704
myotube differentiation involved in skeletal muscle regeneration
Wnt signaling pathway
somatic stem cell population maintenance
skeletal muscle cell differentiation
positive regulation of transcription from RNA polymerase II promoter
canonical Wnt signaling pathway
regulation of transforming growth factor beta receptor signaling pathway
beta-catenin-TCF complex assembly
