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BDKRB2 Antibody (OSB00042W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse spinal cord. The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 mL 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instru... View More
Product Details
OSB00042W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Non-human primate,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the c-terminal region of mouse BDKRB2 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: BDKRB2.
Target Information
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; bradykinin receptor, beta 2; DKFZp686O088; kinin B2
Gene Aliases: B(2); B2; B2BKR; B2BRA; B2R; Bdkrb2; BK-2; BK2; BK2R; BKR2; BRB2
UniProt ID: (Mouse) P32299, (Rat) P25023
Entrez Gene ID: (Mouse) 12062, (Rat) 25245
acute inflammatory response to antigenic stimulus
smooth muscle contraction
response to stress
signal transduction
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
negative regulation of cell proliferation
response to salt stress
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
vasoconstriction
vasodilation
negative regulation of blood pressure
arachidonic acid secretion
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
sensory perception of pain
response to drug
cellular response to hypoxia
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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