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Product Details
PA5-120836
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 302-391 of human BDKRB2 (NP_000614.1).
Conjugate
Form
Liquid
Concentration
0.66 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914408
Product Specific Information
Positive test controls include: A-549, MCF7, Mouse liver, Rat liver. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein.
Immunogen sequence: SSCQDERIID VITQIASFMA YSNSCLNPLV YVIVGKRFRK KSWEVYQGVC QKGGCRSEPI QMENSMGTLR TSISVERQIH KLQDWAGSRQ
Target Information
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; bradykinin receptor, beta 2; DKFZp686O088; kinin B2
Gene Aliases: B(2); B2; B2BKR; B2BRA; B2R; BDKRB2; BK-2; BK2; BK2R; BKR2; BRB2
UniProt ID: (Human) P30411, (Mouse) P32299, (Rat) P25023
Entrez Gene ID: (Human) 624, (Mouse) 12062, (Rat) 25245
protease binding
phosphatidylinositol phospholipase C activity
bradykinin receptor activity
protein binding
beta-2 adrenergic receptor binding
type 1 angiotensin receptor binding
protein heterodimerization activity
signal transducer activity
G-protein coupled receptor activity
G-protein coupled receptor
acute inflammatory response to antigenic stimulus
smooth muscle contraction
inflammatory response
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
negative regulation of cell proliferation
response to salt stress
regulation of vasoconstriction
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
vasoconstriction
vasodilation
response to drug
regulation of vascular permeability
negative regulation of blood pressure
arachidonic acid secretion
cellular response to hypoxia
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
response to stress
signal transduction
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress
sensory perception of pain
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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