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BDKRB2 Antibody (711638) in IHC
Sections of human pancreas were dewaxed, microwaved in citric acid and incubated with Anti-BDKRB2 Recombinant Rabbit Superclonal™ Antibody (Product # 711638, 1:500 dilution). Sections were then sequentially treated with biotinylated Anti-rabbit IgG and AB solution. Sections were then developed in AEC and lightly counterstained with hematoxylin.
产品信息
711638
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
克隆号
13HCLC
抗原
Peptide corresponding to human BDKRB2 [aa377-aa391]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2784602
产品详细信息
This antibody is predicted to react with Monkey, Mouse, Cat.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
靶标信息
Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; DKFZp686O088
基因别名: B2R; BDKRB2; BK-2; BK2; BKR2; BRB2
UniProt ID: (Human) P30411
Entrez Gene ID: (Human) 624
acute inflammatory response to antigenic stimulus
smooth muscle contraction
inflammatory response
cell surface receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
negative regulation of cell proliferation
response to salt stress
regulation of vasoconstriction
negative regulation of peptidyl-serine phosphorylation
maintenance of blood-brain barrier
vasoconstriction
vasodilation
response to drug
regulation of vascular permeability
negative regulation of blood pressure
arachidonic acid secretion
cellular response to hypoxia
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
