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产品信息
PA5-83044
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.08 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790200
产品详细信息
Immunogen sequence: GRRFTMGERI GAIKQESEEP PTKKNRMQLS DDEGHFTSSD LISSPFLGPH PHQPPFCLPF YLIPPSATAY LPMLEKCWYP TSVPVLYPGL NASAAALSSF MNPDKISAPL LMPQRLPSPL PAHPSVDSSV LLQ
靶标信息
Differentiated embryo-chondrocyte expressed gene 1 (DEC1) is an important protein involved in embryonic cell differentiation, proliferation, and apoptosis. It has also recently been shown to be regulated by hypoxia. The loss of DEC1 expression may be an early event in the development of lung cancer, while DEC1 may be up-regulated by hypoxia in other cancers and in more extreme hypoxia it may have a role in cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-Dec; basic helix-loop-helix domain containing, class B, 2; basic helix-loop-helix family, member e40; bHLHb2; bHLHe40; Class B basic helix-loop-helix protein 2; Class E basic helix-loop-helix protein 40; DEC1; differentially expressed in chondrocytes 1; Differentially expressed in chondrocytes protein 1; differentiated embryo chondrocyte expressed gene 1; Enhancer-of-split and hairy-related protein 2; FLJ99214; SHARP-2; Stimulated by retinoic acid gene 13 protein
基因别名: BHLHB2; BHLHE40; DEC1; HLHB2; SHARP-2; SHARP2; STRA13; Stra14
UniProt ID: (Human) O14503
Entrez Gene ID: (Human) 8553
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor activity
protein binding
protein domain specific binding
protein homodimerization activity
bHLH transcription factor binding
MRF binding
protein heterodimerization activity
E-box binding
basic helix-loop-helix transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
circadian regulation of gene expression
entrainment of circadian clock by photoperiod
negative regulation of sequence-specific DNA binding transcription factor activity
negative regulation of transcription, DNA-templated
