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BHLHE41 Antibody (PA5-87982) in WB
Western blot analysis of BHLHE41 in various lysates. Samples were incubated with BHLHE41 Polyclonal antibody (Product # PA5-87982) using a dilution of 1:1,500, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-87982
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 120-280 of human BHLHE41 (NP_1103891)
偶联物
形式
Liquid
浓度
1.83 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804562
产品详细信息
Immunogen sequence: LKSPIQSDLD AFHSGFQTCA KEVLQYLSRF ESWTPREPRC VQLINHLHAV ATQFLPTPQL LTQQVPLSKG TGAPSAAGSA AAPCLERAGQ KLEPLAYCVP VIQRTQPSAE LAAENDTDTD SGYGGEAEAR PDREKGKGAG ASRVTIKQEP PGEDSPAPKR M; Positive Samples: NCI-H460, Mouse skeletal muscle, Mouse brain, Mouse lung, Rat skeletal muscle; Cellular Location: Nucleus
靶标信息
BHLHE41 may be a transcriptional repressor that represses both basal and activated transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-Dec; basic helix-loop-helix domain containing, class B, 3; basic helix-loop-helix domain containing, class B3; basic helix-loop-helix family, member e41; bHLHb3; bHLHe41; Class B basic helix-loop-helix protein 3; Class E basic helix-loop-helix protein 41; Differentially expressed in chondrocytes protein 2; Enhancer-of-split and hairy-related protein 1; hDEC2; SHARP-1
基因别名: BHLHB3; BHLHE41; DEC2; hDEC2; SHARP-1; SHARP1
UniProt ID: (Human) Q9C0J9
Entrez Gene ID: (Human) 79365, (Rat) 117095
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription corepressor activity
protein binding
protein homodimerization activity
histone deacetylase binding
bHLH transcription factor binding
MRF binding
protein heterodimerization activity
E-box binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
protein dimerization activity
N-box binding
basic helix-loop-helix transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
cell proliferation
organ morphogenesis
negative regulation of myotube differentiation
negative regulation of transcription by competitive promoter binding
cell differentiation
circadian regulation of gene expression
negative regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
nervous system development
circadian rhythm
entrainment of circadian clock
regulation of neuronal synaptic plasticity
