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产品信息
H00000329-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BIRC2 (NP_001157.1, 1 a.a. approximately 618 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MHKTASQRLF PGPSYQNIKS IMEDSTILSD WTNSNKQKMK YDFSCELYRM STYSTFPAGV PVSERSLARA GFYYTGVNDK VKCFCCGLML DNWKLGDSPI QKHKQLYPSC SFIQNLVSAS LGSTSKNTSP MRNSFAHSLS PTLEHSSLFS GSYSSLSPNP LNSRAVEDIS SSRTNPYSYA MSTEEARFLT YHMWPLTFLS PSELARAGFY YIGPGDRVAC FACGGKLSNW EPKDDAMSEH RRHFPNCPFL ENSLETLRFS ISNLSMQTHA ARMRTFMYWP SSVPVQPEQL ASAGFYYVGR NDDVKCFCCD GGLRCWESGD DPWVEHAKWF PRCEFLIRMK GQEFVDEIQG RYPHLLEQLL STSDTTGEEN ADPPIIHFGP GESSSEDAVM MNTPVVKSAL EMGFNRDLVK QTVQSKILTT GENYKTVNDI VSALLNAEDE KREEEKEKQA EEMASDDLSL IRKNRMALFQ QLTCVLPILD NLLKANVINK QEHDIIKQKT QIPLQARELI DTILVKGNAA ANIFKNCLKE IDSTLYKNLF VDKNMKYIPT EDVSGLSLEE QLRRLQEERT CKVCMDKEVS VVFIPCGHLV VCQECAPSLR KCPICRGIIK GTVRTFLS
靶标信息
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis inhibitor 1; baculoviral IAP repeat-containing 2; Baculoviral IAP repeat-containing protein 2; C-IAP1; Cellular inhibitor of apoptosis 1; hIAP-2; IAP homolog B; IAP-2; Inhibitor of apoptosis protein 2; NFR2-TRAF signalling complex protein; RING finger protein 48; RING-type E3 ubiquitin transferase BIRC2; TNFR2-TRAF-signaling complex protein 2
基因别名: API1; BIRC2; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
UniProt ID: (Human) Q13490
Entrez Gene ID: (Human) 329
protein polyubiquitination
response to hypoxia
placenta development
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular component disassembly involved in execution phase of apoptosis
cell surface receptor signaling pathway
I-kappaB kinase/NF-kappaB signaling
regulation of tumor necrosis factor-mediated signaling pathway
regulation of necrotic cell death
tumor necrosis factor-mediated signaling pathway
regulation of toll-like receptor signaling pathway
TRIF-dependent toll-like receptor signaling pathway
NIK/NF-kappaB signaling
regulation of RIG-I signaling pathway
regulation of cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of innate immune response
response to ethanol
regulation of cell differentiation
regulation of inflammatory response
protein heterooligomerization
response to cAMP
regulation of cell cycle
regulation of necroptotic process
necroptotic process
regulation of nucleotide-binding oligomerization domain containing signaling pathway
mitotic spindle assembly
negative regulation of ripoptosome assembly involved in necroptotic process
positive regulation of protein K63-linked ubiquitination
positive regulation of protein K48-linked ubiquitination
positive regulation of protein monoubiquitination
inhibition of cysteine-type endopeptidase activity involved in apoptotic process
regulation of cysteine-type endopeptidase activity
regulation of reactive oxygen species metabolic process
