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产品信息
PA5-139976
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human BLOC1S3
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2926978
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: LPPLVVQRES AEEAWGTEEA PAPAPARSLL QLRLAES
靶标信息
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: biogenesis of lysosomal organelles complex-1, subunit 3; Biogenesis of lysosome-related organelles complex 1 subunit 3; biogenesis of lysosome-related organelles complex-1, subunit 3; BLOC-1 subunit 3; reduced pigmentation, mouse, homolog of
基因别名: BLOC1S3; BLOS3; HPS8; RP
UniProt ID: (Human) Q6QNY0
Entrez Gene ID: (Human) 388552
eye development
anterograde axonal transport
platelet activation
neuron projection development
melanosome transport
melanosome organization
positive regulation of natural killer cell activation
secretion of lysosomal enzymes
endosome to melanosome transport
response to drug
pigmentation
anterograde synaptic vesicle transport
platelet dense granule organization
protein transmembrane transport
