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BMAL1 Antibody (PA5-118965) in IHC (P)
Immunohistochemistry analysis of BMAL1 in paraffin-embedded Rat Adrenal gland tissue. Samples were incubated with polyclonal antibody (Product # PA5-118965) at a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
产品信息
PA5-118965
产品规格
种属反应
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Aryl Hydrocarbon Receptor Nuclear Translocator Like Protein. The antigen corresponds to amino acid range 1-169 of the target protein.
偶联物
形式
Liquid
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903465
靶标信息
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic helix-loop-helix ARNT-like protein 1; Brain and muscle ARNT-like 1; CG8727 PA; cycle; MGC47515; Tic
基因别名: Arntl; Bmal1; Tic
UniProt ID: (Rat) Q9EPW1
Entrez Gene ID: (Rat) 29657
transcription regulatory region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding
core promoter sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II transcription factor binding
DNA binding
transcription factor activity, sequence-specific DNA binding
signal transducer activity
aryl hydrocarbon receptor binding
bHLH transcription factor binding
sequence-specific DNA binding
protein heterodimerization activity
protein dimerization activity
Hsp90 protein binding
E-box binding
basic helix-loop-helix transcription factor
protein import into nucleus, translocation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
signal transduction
spermatogenesis
circadian rhythm
negative regulation of TOR signaling
circadian regulation of gene expression
regulation of protein catabolic process
regulation of hair cycle
regulation of circadian rhythm
positive regulation of circadian rhythm
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of fat cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of neurogenesis
regulation of insulin secretion
regulation of cell cycle
response to redox state
positive regulation of canonical Wnt signaling pathway
oxidative stress-induced premature senescence
regulation of type B pancreatic cell development
negative regulation of glucocorticoid receptor signaling pathway
regulation of cellular senescence
positive regulation of skeletal muscle cell differentiation
