Invitrogen

BMAL1 Polyclonal Antibody

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BMAL1 Antibody in Western Blot (WB)

BMAL1 Antibody in Western Blot (WB)

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BMAL1 Antibody (PA5-68758) in WB

Western blot analysis of BMAL1 on mouse NIH-3T3 cells. The sample was probed with a BMAL1 polyclonal antibody (Product # PA5-68758) using a primary antibody dilution of 1.25 µg/mL.

BMAL1 Antibody in Western Blot (WB)

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BMAL1 Antibody in Western Blot (WB) — Western blot analysis of BMAL1 on mouse NIH-3T3 cells. The sample was probed with a BMAL1 polyclonal antibody (Product # PA5-68758) using a primary antibody dilution of 1.25 µg/mL.

产品信息

PA5-68758

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1.25 µg/mL

-

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

synthetic peptide directed towards the N terminal region of mouse BMAL1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2691410

产品详细信息

This target displays homology in the following species: Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 93%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%

靶标信息

The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This complex binds an E-box upstream of the PER1 gene, activating this gene and possibly other circadian rhythym-associated genes. Three transcript variants encoding two different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Arnt3; Aryl hydrocarbon receptor nuclear translocator-like protein 1; Basic helix-loop-helix ARNT-like protein 1; Brain and muscle ARNT-like 1; CG8727 PA; cycle; MGC47515

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基因别名: Arnt3; Arntl; bHLHe5; Bmal1; BMAL1b; bmal1b'; MOP3

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UniProt ID: (Mouse) Q9WTL8

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Entrez Gene ID: (Mouse) 11865

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transcription regulatory region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding core promoter sequence-specific DNA binding core promoter binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding signal transducer activity protein binding transcription factor binding aryl hydrocarbon receptor binding bHLH transcription factor binding sequence-specific DNA binding protein heterodimerization activity protein dimerization activity Hsp90 protein binding E-box binding basic helix-loop-helix transcription factor

protein import into nucleus, translocation transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter signal transduction spermatogenesis circadian rhythm negative regulation of TOR signaling circadian regulation of gene expression regulation of protein catabolic process regulation of hair cycle positive regulation of circadian rhythm proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of fat cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter rhythmic process regulation of neurogenesis regulation of insulin secretion regulation of cell cycle response to redox state positive regulation of canonical Wnt signaling pathway oxidative stress-induced premature senescence regulation of type B pancreatic cell development negative regulation of glucocorticoid receptor signaling pathway regulation of cellular senescence positive regulation of skeletal muscle cell differentiation