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产品信息
PA5-118984
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein BMP Binding Endothelial Regulator. The antigen corresponds to amino acid range 40-298 of the target protein.
偶联物
形式
Liquid
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903484
靶标信息
This gene encodes a secreted protein that interacts with, and inhibits bone morphogenetic protein (BMP) function. It has been shown to inhibit BMP2- and BMP4-dependent osteoblast differentiation and BMP-dependent differentiation of the chondrogenic cells. Mutations in this gene are associated with a lethal skeletal disorder, diaphanospondylodysostosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP-Binding Endothelial Regulator Protein; Bone morphogenetic protein-binding endothelial cell precursor-derived regulator; CRIM3; crossveinless-2; mCV2; Protein crossveinless-2
基因别名: 3110056H04Rik; Bmper; Crim3; CV-2; Cv2
UniProt ID: (Mouse) Q8CJ69
Entrez Gene ID: (Mouse) 73230
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
regulation of endothelial cell migration
negative regulation of BMP signaling pathway
endothelial cell activation
endothelial cell differentiation
inner ear development
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of ERK1 and ERK2 cascade
