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产品信息
BMS147BT
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
VAA-33
偶联物
形式
Liquid
浓度
10 µL/Test
纯化类型
Affinity chromatography
保存液
TBS, pH 7.2-7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
2-8°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10609473
产品详细信息
Description: BMS147 specifically recognizes Annexin V (VAC- alpha ). BMS147 is suitable for ELISA application, Western blot analysis and is suitable as primary antibody for staining in FACS analysis.
BMS147FI can be used for direct staining of cells.
BMS147BT can be used in a two-step procedure using the biotin-(strept-)avidin system. For intracellular stainings the use of BMS147FI is recommended.
Applications Tested: Flow Cytometry (Intracellular Staining).
Purity: >95%.
靶标信息
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Anchorin CII; Annexin A5; Annexin V; Annexin-5; Calphobindin I; CBP-I; CPB-I; Endonexin II; epididymis secretory protein Li 7; Lipocortin V; PAP-I; Placental anticoagulant protein 4; Placental anticoagulant protein I; PP4; Thromboplastin inhibitor; VAC-alpha; Vascular anticoagulant-alpha
基因别名: ANX5; ANXA5; ENX2; HEL-S-7; PP4; RPRGL3
UniProt ID: (Human) P08758
Entrez Gene ID: (Human) 308
positive regulation of defense response to virus by host
signal transduction
blood coagulation
negative regulation of blood coagulation
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of catalytic activity
protein homooligomerization
response to calcium ion
calcium ion transmembrane transport
cellular response to lead ion
response to thyroid hormone
cellular response to gonadotropin-releasing hormone
mitophagy in response to mitochondrial depolarization
xenophagy
regulation of sperm motility
negative regulation of prolactin secretion
