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BPNT1 Antibody (PA5-28168) in IHC (P)
BPNT1 Polyclonal Antibody detects BPNT1 protein at cytosol on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. BPNT1 Polyclonal Antibody (Product # PA5-28168) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-28168
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 35 and 306 of Human BPNT1
偶联物
形式
Liquid
浓度
0.7 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545644
产品详细信息
Recommended positive controls: HeLaS3, mouse liver.
Predicted reactivity: Mouse (93%), Rat (94%), Xenopus laevis (84%), Chicken (83%), Bovine (93%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; Bisphosphate 3'-nucleotidase 1; BPntase; BPntase 1; epididymis luminal protein 20; HsPIP; Inositol-polyphosphate 1-phosphatase; PAP phosphatase; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; testicular tissue protein Li 29
基因别名: BPNT1; BPntase; HEL20; PIP
UniProt ID: (Human) O95861, (Mouse) Q9Z0S1
Entrez Gene ID: (Human) 10380, (Mouse) 23827
