Invitrogen

BRIP1 Monoclonal Antibody (GO11-1A3)

产品信息

37-0900

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

免疫细胞化学 (ICC/IF)

Assay-dependent

流式细胞分析 (Flow)

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免疫沉淀 (IP)

Assay-dependent

产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

GO11-1A3

抗原

BACH1/GST fusion protein encompassing the C-terminus of human BACH1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.1% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2533297

靶标信息

LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Recapitulation of erythropoiesis in congenital dyserythropoietic anaemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities.

Haematologica

Scott C,Downes DJ,Brown JM,Beagrie R,Olijnik AA,Gosden M,Schwessinger R,Fisher CA,Rose A,Ferguson DJP,Johnson E,Hill QA,Okoli S,Renella R,Ryan K,Brand M,Hughes J,Roy NBA,Higgs DR,Babbs C,Buckle VJ

37-0900 was used in Flow Cytometry to provide important pointers to the pathways affected in CDA-I which for the first time can now be pursued in the tractable culture system utilised here.

Mon Nov 01 00:00:00 UTC 2021

生物信息学

蛋白别名: ATP-dependent RNA helicase BRIP1; BACH 1; BACH1 BRIP1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; BRCA1-interacting protein 1; BRCA1-interacting protein C-terminal helicase 1; BRCA1/BRCA2-associated helicase 1; BRIP 1; DNA 5'-3' helicase FANCJ; FANCJ protein; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523

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基因别名: BACH1; BRIP1; FANCJ; OF

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UniProt ID: (Human) Q9BX63

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Entrez Gene ID: (Human) 83990

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功能

DNA binding ATP-dependent DNA helicase activity protein binding ATP binding metal ion binding 4 iron, 4 sulfur cluster binding DNA helicase

参与通路

DNA damage checkpoint DNA synthesis involved in DNA repair strand displacement DNA replication double-strand break repair regulation of transcription from RNA polymerase II promoter negative regulation of cell proliferation DNA duplex unwinding cellular response to vitamin regulation of signal transduction by p53 class mediator