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产品信息
PA5-41893
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of human BRUNOL4
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2605630
产品详细信息
Peptide sequence: PMAAFAAAQM QQMAALNMNG LAAAPMTPTS GGSTPPGITA PAVPSIPSPI
Sequence homology: Cow: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene.
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生物信息学
蛋白别名: Bruno -like 4; bruno-like 4, RNA binding protein; Bruno-like protein 4; CELF-4; CUG-BP and ETR-3 like factor 4; CUG-BP- and ETR-3-like factor 4; CUGBP; CUGBP Elav-like family member 4; LYST-interacting protein LIP9; RNA-binding protein BRUNOL-4; RNA-binding protein BRUNOL4
基因别名: BRUNOL4; CELF-4; CELF4
UniProt ID: (Human) Q9BZC1
Entrez Gene ID: (Human) 56853
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splice site selection
germ cell development
embryo development
negative regulation of translation
negative regulation of mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome
negative regulation of excitatory postsynaptic potential
