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产品信息
PA5-98979
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Butyrophilin-like protein 2 protein (26-202AA)
偶联物
形式
Liquid
浓度
4 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2813592
靶标信息
BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BTL-II; butyrophilin-like 2 (MHC class II associated); Butyrophilin-like protein 2; butyrophylin-like MHC class II associated
基因别名: BTL-II; Btl2; BTLN2; BTN7; BTNL2; Gm315; HSBLMHC1; NG9; SS2
UniProt ID: (Human) Q9UIR0, (Mouse) O70355
Entrez Gene ID: (Human) 56244, (Mouse) 547431
