Product References
Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1.
Journal of biochemical and molecular toxicology
Abdelrahman RS,Abdelsalam RA,Zaghloul MS
PA5-20068 was used in Immunohistochemistry (Paraffin), Western Blot to investigate the impact of trimetazidine (a metabolic modulator-antianginal drug), against folic acid-induced acute kidney injury.
Sun May 01 00:00:00 UTC 2022
Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1.
Journal of biochemical and molecular toxicology
Abdelrahman RS,Abdelsalam RA,Zaghloul MS
PA5-20068 was used in Immunohistochemistry (Paraffin), Western Blot to investigate the impact of trimetazidine (a metabolic modulator-antianginal drug), against folic acid-induced acute kidney injury.
Sun May 01 00:00:00 UTC 2022
Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis.
Bioengineered
Li J,Bai J,Tuerdi N,Liu K
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Western Blot
Fri Apr 01 00:00:00 UTC 2022
Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis.
Bioengineered
Li J,Bai J,Tuerdi N,Liu K
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Western Blot
Fri Apr 01 00:00:00 UTC 2022
GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia.
International journal of molecular sciences
Marwarha G,Røsand Ø,Slagsvold KH,Høydal MA
PA5-20068 was used in ELISA to unveil that the inhibition of GSK3β kinase activity is indispensable in mediating the miR-210-orchestrated protective cellular response to hypoxia-induced apoptotic cell death.
Fri Aug 19 00:00:00 UTC 2022
The protective effect of Ganoderma lucidum on testicular torsion/detorsion-induced ischemia-reperfusion (I/R) injury.
Acta cirurgica brasileira
Doğan G,İpek H
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Immunohistochemistry
Fri May 01 00:00:00 UTC 2020
Small-Dose Sunitinib Modulates p53, Bcl-2, STAT3, and ERK1/2 Pathways and Protects against Adenine-Induced Nephrotoxicity.
Pharmaceuticals (Basel, Switzerland)
Saleh MA,Awad AM,Ibrahim TM,Abu-Elsaad NM
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Immunohistochemistry
Tue Nov 17 00:00:00 UTC 2020
Small-Dose Sunitinib Modulates p53, Bcl-2, STAT3, and ERK1/2 Pathways and Protects against Adenine-Induced Nephrotoxicity.
Pharmaceuticals (Basel, Switzerland)
Saleh MA,Awad AM,Ibrahim TM,Abu-Elsaad NM
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Immunohistochemistry
Tue Nov 17 00:00:00 UTC 2020
BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models.
Cell death & disease
Vervloessem T,Sasi BK,Xerxa E,Karamanou S,Kale J,La Rovere RM,Chakraborty S,Sneyers F,Vogler M,Economou A,Laurenti L,Andrews DW,Efremov DG,Bultynck G
PA5-20068 was used in Western Blotting to study the therapeutic potential and mechanism of action of BDA-366 in chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL).
Thu Sep 17 00:00:00 UTC 2020
BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models.
Cell death & disease
Vervloessem T,Sasi BK,Xerxa E,Karamanou S,Kale J,La Rovere RM,Chakraborty S,Sneyers F,Vogler M,Economou A,Laurenti L,Andrews DW,Efremov DG,Bultynck G
PA5-20068 was used in Western Blotting to study the therapeutic potential and mechanism of action of BDA-366 in chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL).
Thu Sep 17 00:00:00 UTC 2020
Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways.
Scientific reports
Awad AM,Saleh MA,Abu-Elsaad NM,Ibrahim TM
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Immunohistochemistry
Mon Jul 13 00:00:00 UTC 2020
Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways.
Scientific reports
Awad AM,Saleh MA,Abu-Elsaad NM,Ibrahim TM
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Immunohistochemistry
Mon Jul 13 00:00:00 UTC 2020
The AKT/BCL-2 Axis Mediates Survival of Uterine Leiomyoma in a Novel 3D Spheroid Model.
Endocrinology
Vidimar V,Chakravarti D,Bulun SE,Yin P,Nowak R,Wei JJ,Kim JJ
PA5-20068 was used in Immunohistochemistry to conclude BCL-2 mediates AKT survival of ULM, providing compelling evidence for further evaluation of BH3 mimetics for ULM treatment.
Thu Mar 01 00:00:00 UTC 2018
TMEM119 silencing inhibits cell viability and causes the apoptosis of gastric cancer SGC-7901 cells.
Oncology letters
Zheng P,Wang W,Ji M,Zhu Q,Feng Y,Zhou F,He Q
Published figure using Bcl-2 polyclonal antibody (Product # PA5-20068) in Western Blot
Fri Jun 01 00:00:00 UTC 2018
Inhibition of endoplasmic reticulum stress in high-fat-diet-induced obese C57BL/6 mice: Efficacy of a novel extract from mulberry (Morus alba) leaves fermented with Cordyceps militaris.
Laboratory animal research
Lee MR,Bae SJ,Kim JE,Song BR,Choi JY,Park JJ,Park JW,Kang MJ,Choi HJ,Choi YW,Kim KM,Hwang DY
PA5-20068 was used in Western Blotting to provide the first evidence that EMfC with the anti-obesity effects can be suppressed ER stress and ER stress-induced apoptosis in the hepatic steatosis of HFD-induced obesity model.
Sat Dec 01 00:00:00 UTC 2018