Invitrogen

Bcl-3 Monoclonal Antibody (Ham 150-3.5), Biotin

查看其他13个BCL-3抗体

产品信息

MA5-17665

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-dependent

-

酶联免疫吸附实验 (ELISA)

Assay-dependent

-

产品规格

种属反应

Mouse

宿主/亚型

Armenian hamster / IgG

分类

Monoclonal

类型

Antibody

克隆号

Ham 150-3.5

抗原

recombinant Bcl-3-6-histidine tag

偶联物

Biotin Biotin Biotin

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Protein G

保存液

PBS with 4-5mg/mL BSA

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2539055

靶标信息

B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein homolog; BCL-3; Bcl-3 protein

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基因别名: AI528691; Bcl-3; Bcl3

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UniProt ID: (Mouse) Q9Z2F6

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Entrez Gene ID: (Mouse) 12051

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DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding membrane traffic protein

protein import into nucleus, translocation follicular dendritic cell differentiation marginal zone B cell differentiation humoral immune response mediated by circulating immunoglobulin germinal center formation transcription, DNA-templated regulation of transcription, DNA-templated cellular response to DNA damage stimulus I-kappaB kinase/NF-kappaB signaling response to virus response to UV-C antimicrobial humoral response extracellular matrix organization DNA damage response, signal transduction by p53 class mediator positive regulation of interferon-gamma production T-helper 1 type immune response negative regulation of tumor necrosis factor biosynthetic process defense response to bacterium intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator defense response to protozoan regulation of apoptotic process negative regulation of apoptotic process T-helper 2 cell differentiation positive regulation of interleukin-10 biosynthetic process negative regulation of interleukin-8 biosynthetic process positive regulation of translation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter spleen development