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Product Details
PA1-46312
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to internal residues 200-300 of the human beclin 2. [NCBI# XP_945075]
Conjugate
Form
Liquid
Concentration
1.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 30% glycerol
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_1089712
Product Specific Information
Suggested positive control: 293 whole cell lysate, HEK293 kidney cell lysates and MCC827 lung cell lysates.
Does not appear to work with A431 lysates.
Target Information
Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bcl-2; BCS2; beclin 1, autophagy related, pseudogene 1; Beclin-1 autophagy-related pseudogene 1; Beclin-1-like protein 1; Beclin-2; PFM 2; PFM2; PRDM 5; PRDM5; PRDM5 protein
Gene Aliases: Beclin-2; BECN1L1; BECN1P1; BECN2; Gm104
UniProt ID: (Human) A8MW95, (Mouse) P0DM65
Entrez Gene ID: (Human) 441925, (Mouse) 226720
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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