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Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Bestrophin 3.
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bestrophin-3; vitelliform macular dystrophy 2-like 3; Vitelliform macular dystrophy 2-like protein 3
基因别名: Best3; mBest4; Vmd2l3
UniProt ID: (Mouse) Q6H1V1
Entrez Gene ID: (Mouse) 382427