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产品信息
PA5-82066
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2789227
产品详细信息
Immunogen sequence: RGFWDFTLDD GPFMMNDEEA SGADTSGVLD PDSVTPTYSA MCPFGCHCHL RVVQCSDLGL KSVPKEISPD TTLLDLQNND ISELRKDDFK GLQHLYALVL VNNKISKIHE KAFSPLRKLQ KLYISKNHLV EIPPNLPSSL
靶标信息
BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transferring growth factor-beta. It may promote neuronal survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Biglycan; Bone/cartilage proteoglycan I; bone/cartilage proteoglycan-I; dermatan sulphate proteoglycan I; PG S1; PG-S1; small leucine-rich protein 1A
基因别名: BGN; DSPG1; PG-S1; PGI; SLRR1A
UniProt ID: (Human) P21810
Entrez Gene ID: (Human) 633
blood vessel remodeling
negative regulation of protein kinase activity
biological_process
cytokine-mediated signaling pathway
peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
extracellular matrix organization
glycosaminoglycan metabolic process
chondroitin sulfate biosynthetic process
chondroitin sulfate catabolic process
dermatan sulfate biosynthetic process
negative regulation of JAK-STAT cascade
