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产品信息
MA1-826
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
18F8
抗原
Synthetic peptide corresponding to residues M(1) H R L L A W D A A C L P P P A A F P K L H(21) of mouse C/EBP beta.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2276066
产品详细信息
MA1-826 detects C/EBP beta protein in human, mouse, and rat samples. MA1-826 only detects the LAP* isoform of C/EBP beta.
MA1-826 has successfully been used in Western blot, immunofluorescent and immunoprecipitation procedures. By Western blot, this antibody detects a 37 kDa protein representing LAP* of C/EBP beta (N-terminus fragment) in transfected 293T cells.
The MA1-826 immunogen is a synthetic peptide corresponding to residues M(1) H R L L A W D A A C L P P P A A F P K L H(21) of mouse C/EBP beta. This peptide (Cat. # PEP-243) is available for use in neutralization and control experiments.
靶标信息
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AGP/EBP; C EBP; C/EBP BETA; C/EBP-related protein 2; CCAAT/enhancer binding protein (C/EBP), beta; CCAAT/enhancer-binding protein beta; IL-6DBP; interleukin 6-dependent DNA-binding protein; Interleukin-6-dependent-binding protein; LAP; LIP; Liver activator protein; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; Nuclear factor NF-IL6; nuclear factor of interleukin 6; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; Silencer factor B; TCF-5; Transcription factor 5; transcription factor C/EBP beta
基因别名: C/EBP-beta; C/EBPbeta; CEBPB; CRP2; IL-6DBP; IL6DBP; LAP; LIP; NF-IL6; NF-M; Nfil6; PP9092; Sfb; TCF5
UniProt ID: (Human) P17676, (Mouse) P28033, (Rat) P21272
Entrez Gene ID: (Human) 1051, (Mouse) 12608, (Rat) 24253
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
kinase binding
histone acetyltransferase binding
glucocorticoid receptor binding
protein homodimerization activity
histone deacetylase binding
ubiquitin-like protein ligase binding
protein heterodimerization activity
sequence-specific DNA binding
ovarian follicle development
embryonic placenta development
granuloma formation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell differentiation
neuron differentiation
response to lipopolysaccharide
positive regulation of interleukin-4 production
mammary gland epithelial cell proliferation
response to endoplasmic reticulum stress
T-helper 1 cell activation
negative regulation of T cell proliferation
defense response to bacterium
negative regulation of neuron apoptotic process
regulation of interleukin-6 biosynthetic process
fat cell differentiation
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
brown fat cell differentiation
mammary gland epithelial cell differentiation
regulation of transcription involved in cell fate commitment
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to amino acid stimulus
hepatocyte proliferation
liver regeneration
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
acute-phase response
inflammatory response
immune response
memory
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to organic cyclic compound
