Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA1-827
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1H7
抗原
Recombinant mouse LIP.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2078054
产品详细信息
MA1-827 detects C/EBP beta protein in mouse and rat samples. MA1-827 detects the LAP*, LAP and LIP isoforms of C/EBP beta.
MA1-827 has successfully been used in Western blot, immunofluorescent and immunoprecipitation procedures. By Western blot, this antibody detects 38, 35 and 20 kDa proteins representing C/EBP beta LAP*, LAP, and LIP isoforms respectively, in 3T3-L1 cells. LIP is recognized as the C-terminus fragment. Immunofluorescent staining of C/EBP beta in P388D1 cells can be performed using MA1-827
The MA1-827 immunogen is recombinant mouse LIP.
靶标信息
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AGP/EBP; C EBP; C/EBP BETA; C/EBP-related protein 2; CCAAT/enhancer-binding protein beta; IL-6DBP; Interleukin-6-dependent-binding protein; LAP; LIP; Liver-enriched inhibitory protein; Liver-enriched transcriptional activator; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; Silencer factor B
基因别名: C/EBPbeta; Cebpb; CRP2; IL-6DBP; Il6dbp; LAP; LIP; NF-IL6; NF-M; Nfil6; Sfb; TCF5
UniProt ID: (Mouse) P28033, (Rat) P21272
Entrez Gene ID: (Mouse) 12608, (Rat) 24253
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
transcription factor binding
kinase binding
histone acetyltransferase binding
glucocorticoid receptor binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
ubiquitin-like protein ligase binding
protein heterodimerization activity
ovarian follicle development
embryonic placenta development
granuloma formation
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell differentiation
neuron differentiation
response to lipopolysaccharide
positive regulation of interleukin-4 production
mammary gland epithelial cell proliferation
response to endoplasmic reticulum stress
T-helper 1 cell activation
negative regulation of T cell proliferation
defense response to bacterium
negative regulation of neuron apoptotic process
regulation of interleukin-6 biosynthetic process
fat cell differentiation
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
brown fat cell differentiation
mammary gland epithelial cell differentiation
regulation of transcription involved in cell fate commitment
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to amino acid stimulus
hepatocyte proliferation
liver regeneration
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
