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产品信息
PA5-36260
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the N-terminus of human C/EBP zeta
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553445
产品详细信息
This antibody detects endogenous protein at a molecular weight of 121 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurrence of acute myeloid leukemia (AML).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C EBP; C/EBP zeta; CBF; CCAAT-binding factor; CCAAT-box-binding transcription factor; CCAAT/enhancer binding protein (C/EBP), zeta; CCAAT/enhancer binding protein alpha (C/EBP) related sequence 1; CCAAT/enhancer binding protein cebp family zeta; CCAAT/enhancer-binding protein zeta; CEBP zeta; core-binding factor; CTF2; HSPCBF
基因别名: AI848081; CBF; CBF2; Cebpa-rs1; CEBPZ; HSP-CBF; NOC1
UniProt ID: (Human) Q03701, (Mouse) P53569
Entrez Gene ID: (Human) 10153, (Mouse) 12607, (Rat) 362686
