Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 4
C1 inhibitor Antibody (PA5-119744) in IHC (P)
Immunohistochemistry (Paraffin) analysis of paraffin-embedded human placenta tissue using C1 inhibitor Polyclonal Antibody (Product # PA5-119744). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the C1 inhibitor antibody a... View More
产品信息
PA5-119744
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within human SERPING1 aa 145-403
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2913316
产品详细信息
Positive Control: HepG2 cell lysate, HL-60 cell lysate, human liver tissue, human placenta tissue, mouse liver tissue.
Subcellular Location: Secreted.
靶标信息
C1-inhibitor (C1INH) functions as a regulator of the activation of the classical complement pathway and of the contact activation system of kinin generation and coagulation. Its primary biologically relevant target proteinases are C1r, C1s, coagulation factors XIa and XIIa, and plasma kallikrein. C1-inhibitor consists of one polypeptide chain and has a molecular mass of ~104 kDa. Serum concentration has been determined to 180 µg/mL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; complement component 1 inhibitor; esterase inhibitor; IC1; Plasma protease C1 inhibitor; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G, member 1; serine/cysteine proteinase inhibitor clade G member 1; Serpin G1; serpin peptidase inhibitor clade G member 1; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
基因别名: C1IN; C1INH; C1NH; HAE1; HAE2; SERPING1
UniProt ID: (Human) P05155, (Mouse) P97290
Entrez Gene ID: (Human) 710, (Mouse) 12258
negative regulation of complement activation, lectin pathway
platelet degranulation
complement activation, classical pathway
aging
blood coagulation, intrinsic pathway
blood circulation
negative regulation of endopeptidase activity
fibrinolysis
innate immune response
immune system process
blood coagulation
hemostasis
negative regulation of peptidase activity
regulation of blood coagulation
negative regulation of complement activation
