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Immunogen sequence: ESEDGMRTRPG DGSHRRGQSP LPRQRFPVPD SVLNMFPGTE EGPEDDSTKH GGRVRTFPHE RGNWATHVYV PYEAKEEFLD LLD
Highest antigen sequence identity to the following orthologs - mouse 70%, rat 75%.
C16orf57 is a phosphodiesterase responsible for the U6 snRNA 3' end processing. This protein acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.
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Protein Aliases: 3'-5' RNA exonuclease USB1; FLJ13154; hUsb1; HVSL motif containing 1; Mutated in PN protein 1; Mutated in poikiloderma with neutropenia protein 1; putative U6 snRNA phosphodiesterase; U six biogenesis 1; U6 snRNA biogenesis 1; U6 snRNA phosphodiesterase 1; UPF0406 protein C16orf57; USB1
Gene Aliases: C16orf57; hUsb1; HVSL1; Mpn1; PN; USB1
UniProt ID: (Human) Q9BQ65
Entrez Gene ID: (Human) 79650
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