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产品信息
PA5-43904
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human C1orf96 (aa 35-84).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2607287
产品详细信息
Peptide sequence: LGRRLLEQAH APWLWDDWGP AGSSEDSASS ESSGAGGPAP RCAPPSPPPP
Sequence homology: Dog: 79%; Human: 100%
靶标信息
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centriole and spindle-associated protein; Centriole, cilia and spindle-associated protein
基因别名: C1orf96; CCSAP; CSAP
UniProt ID: (Human) Q6IQ19
Entrez Gene ID: (Human) 126731
