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C1orf96 Antibody (PA5-60366) in IHC
Immunohistochemical staining of C1orf96 in human cerebellum, cerebral cortex, kidney and pancreas using C1orf96 Polyclonal Antibody (Product # PA5-60366) (A) shows similar protein distribution across tissues to an independent C1orf96 Polyclonal Antibody (B).
产品信息
PA5-60366
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2638955
产品详细信息
Immunogen sequence: EEQDAEAGDA EAEDAEDAAL PALPVKDVED KPEQQTRTRE TDKSPTSTEP RQQPSALFAR GNRKAVKSPQ RSSSKIKENK HPFALYGW
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 63%.
靶标信息
Plays a role in microtubule (MT) stabilization and this stabilization involves the maintenance of NUMA1 at the spindle poles. Colocalizes with polyglutamylated MTs to promote MT stabilization and regulate bipolar spindle formation in mitosis. Binding of CCSAP to centrosomes and the spindle around centrosomes during mitosis inhibits MT depolymerization, thereby stabilizing the mitotic spindle (PubMed:26562023). May play a role in embryonic development. May be required for proper cilia beating. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: centriole and spindle-associated protein; Centriole, cilia and spindle-associated protein
基因别名: C1orf96; CCSAP; CSAP
UniProt ID: (Human) Q6IQ19
Entrez Gene ID: (Human) 126731
