Invitrogen

C2 Polyclonal Antibody

C2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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C2 Antibody (PA5-119046) in IHC (P)

Immunohistochemistry analysis of C2 in paraffin-embedded Human Thyroid cancer tissue. Samples were incubated with polyclonal antibody (Product # PA5-119046) at a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.

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产品信息

PA5-119046

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.5-2 µg/mL

免疫组化（石蜡） (IHC (P))

5-20 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein Complement Component 2. The antigen corresponds to amino acid range 245-451 of the target protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.88 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C

运输条件

Wet ice

AB_2903546

靶标信息

Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.

仅用于科研。不用于诊断过程。未经明确授权不得转售。