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Product Details
PA5-61096
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human C2orf60
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2639021
Product Specific Information
Immunogen sequence: KRVVLFSPRD AQYLYLKGTK SEVLNIDNPD LAKYPLFSKA RRYECSLEAG DVLFIPALWF HNVISEEFGV GVNIFWKHLP SECYDKTDTY GNKDPTAASR AAQILDRALK TLAELPEEYR DFYARRMV
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
Target Information
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hTYW5; jmjC domain-containing protein C2orf60; tRNA wybutosine-synthesizing protein 5; tRNA yW-synthesizing enzyme 5; tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase
Gene Aliases: C2orf60; hTYW5; TYW5
UniProt ID: (Human) A2RUC4
Entrez Gene ID: (Human) 129450
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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