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Product Details
H00000719-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C3AR1 (NP_004045.1, 1 a.a. approximately 482 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MASFSAETNS TDLLSQPWNE PPVILSMVIL SLTFLLGLPG NGLVLWVAGL KMQRTVNTIW FLHLTLADLL CCLSLPFSLA HLALQGQWPY GRFLCKLIPS IIVLNMFASV FLLTAISLDR CLVVFKPIWC QNHRNVGMAC SICGCIWVVA FVMCIPVFVY REIFTTDNHN RCGYKFGLSS SLDYPDFYGD PLENRSLENI VQPPGEMNDR LDPSSFQTND HPWTVPTVFQ PQTFQRPSAD SLPRGSARLT SQNLYSNVFK PADVVSPKIP SGFPIEDHET SPLDNSDAFL STHLKLFPSA SSNSFYESEL PQGFQDYYNL GQFTDDDQVP TPLVAITITR LVVGFLLPSV IMIACYSFIV FRMQRGRFAK SQSKTFRVAV VVVAVFLVCW TPYHIFGVLS LLTDPETPLG KTLMSWDHVC IALASANSCF NPFLYALLGK DFRKKARQSI QGILEAAFSE ELTRSTHCPS NNVISERNST TV
Target Information
C3AR1 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. The receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C3a anaphylatoxin chemotactic receptor; C3a receptor; C3AR; complement component 3 receptor 1
Gene Aliases: AZ3B; C3AR; C3AR1; C3R1; HNFAG09
UniProt ID: (Human) Q16581
Entrez Gene ID: (Human) 719
complement receptor mediated signaling pathway
tolerance induction to nonself antigen
chemotaxis
inflammatory response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
regulation of blood pressure
positive regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
regulation of complement activation
positive regulation of angiogenesis
positive regulation of smooth muscle cell proliferation
positive regulation of glomerular mesangial cell proliferation
positive regulation of neutrophil chemotaxis
positive regulation of DNA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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