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Invitrogen
C3a Receptor Chimeric Recombinant Rabbit Monoclonal Antibody (3G7)
FIGURE: 1 / 1
C3a Receptor Chimeric Antibody (MA5-47929) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of C3a Receptor in human peripheral blood monocytes (PBMs) using C3a Receptor Chimeric Monoclonal Antibody (Product # MA5-47929). Paraformaldehyde-fixed cells were immobilized on cover slips and stained with C3a Receptor Chimeric Monoclonal Antibody at 10 µg/mL for 1h followed by Alexa Fluor488 secondary antibody (1 µg/mL), showing membrane staining. The nucle... View More
Product Details
MA5-47929
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
3G7
Immunogen
The 2e loop of the C3a receptor.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3074373
Product Specific Information
Specificity: Binds specifically to the 2e loop of the human C3a receptor, residues 185-193.
Target Information
C3AR1 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. The receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. (Uniprot)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C3a anaphylatoxin chemotactic receptor; C3a receptor; C3AR; complement component 3 receptor 1
Gene Aliases: AZ3B; C3AR; C3AR1; C3R1; HNFAG09
UniProt ID: (Human) Q16581
Entrez Gene ID: (Human) 719
complement receptor mediated signaling pathway
tolerance induction to nonself antigen
chemotaxis
inflammatory response
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood circulation
regulation of blood pressure
positive regulation of vascular endothelial growth factor production
positive regulation of macrophage chemotaxis
regulation of complement activation
positive regulation of angiogenesis
positive regulation of smooth muscle cell proliferation
positive regulation of glomerular mesangial cell proliferation
positive regulation of neutrophil chemotaxis
positive regulation of DNA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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