Invitrogen

C9orf72 Monoclonal Antibody (GT1553)

C9orf72 Antibody in Immunocytochemistry (ICC/IF)

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C9orf72 Antibody (MA5-46910) in ICC/IF

Immunofluorescent analysis of C9orf72 in DIV9 rat E18 primary hippocampal neuron cells. Cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: C9orf72 stained by C9orf72 monoclonal antibody (Product # MA5-46910) diluted at 1:250. Red: Tau, an Axon marker, stained by Tau antibody diluted at 1:500. Blue: Fluoroshield with DAPI.

C9orf72 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

MA5-46910

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:1,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

Assay-dependent

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

GT1553

抗原

Recombinant protein encompassing a sequence within the N-terminus region of human C9orf72. The exact sequence is proprietary.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2937982

产品详细信息

Store as concentrated solution.

Centrifuge briefly prior to opening vial.

Positive control: C9orf72-transfected 293T, Neuro2A, NIH-3T3, Raw264.7, C2C12, mouse brain, U87-MG, SK-N-SH, IMR32, SK-N-AS, 293T.

靶标信息

C9orf72 may play a role in endosomal trafficking and autophagy. It is known to interact with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPSases. C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome. Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。