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Sequence of this protein is as follows: MASPDWGYDD KNGPEQWSKL YPIANGNNQS PVDIKTSETK HDTSLKPISV SYNPATAKEI INVGHSFHVN FEDNDNRSVL KGGPFSDSYR LFQFHFHWGS TNEHGSEHTV DGVKYSAELH VAHWNSAKYS SLAEAASKAD GLAVIGVLMK VGEANPKLQK VLDALQAIKT KGKRAPFTNF DPSTLLPSSL DFWTYPGSLT HPPLYESVTW IICKESISVS SEQLAQFRSL LSNVEGDNAV PMQHNNRPTQ PLKGRTVRAS F
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CA I; CA-I; CAB; Carbonate dehydratase I; Carbonic anhydrase 1; Carbonic anhydrase B; Carbonic anhydrase I; Cyanamide hydratase CA1; epididymis secretory protein Li 11
基因别名: AW555628; CA-I; CA1; CAB; Car-1; Car1; HEL-S-11
UniProt ID: (Human) P00915, (Mouse) P13634
Entrez Gene ID: (Human) 759, (Mouse) 12346