Osenses

CACNA1E Polyclonal Antibody

产品信息

OSC00085W-100UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:300-1:2,000

免疫组化 (IHC)

1:300-1:2,000

其他PubMed (Misc)

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Not Applicable

宿主/亚型

Rabbit / Ig

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from c-terminal region of human CACNA1E conjugated to an immunogenic carrier protein was used as the antigen

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

Conc. Not Determined

保存液

whole serum

内含物

no preservative

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

Specificity of this antibody: CACNA1E.

靶标信息

The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The DNA sequence and biological annotation of human chromosome 1.

Nature

Gregory SG,Barlow KF,McLay KE,Kaul R,Swarbreck D,Dunham A,Scott CE,Howe KL,Woodfine K,Spencer CC,Jones MC,Gillson C,Searle S,Zhou Y,Kokocinski F,McDonald L,Evans R,Phillips K,Atkinson A,Cooper R,Jones C,Hall RE,Andrews TD,Lloyd C,Ainscough R,Almeida JP,Ambrose KD,Anderson F,Andrew RW,Ashwell RI,Aubin K,Babbage AK,Bagguley CL,Bailey J,Beasley H,Bethel G,Bird CP,Bray-Allen S,Brown JY,Brown AJ,Buckley D,Burton J,Bye J,Carder C,Chapman JC,Clark SY,Clarke G,Clee C,Cobley V,Collier RE,Corby N,Coville GJ,Davies J,Deadman R,Dunn M,Earthrowl M,Ellington AG,Errington H,Frankish A,Frankland J,French L,Garner P,Garnett J,Gay L,Ghori MR,Gibson R,Gilby LM,Gillett W,Glithero RJ,Grafham DV,Griffiths C,Griffiths-Jones S,Grocock R,Hammond S,Harrison ES,Hart E,Haugen E,Heath PD,Holmes S,Holt K,Howden PJ,Hunt AR,Hunt SE,Hunter G,Isherwood J,James R,Johnson C,Johnson D,Joy A,Kay M,Kershaw JK,Kibukawa M,Kimberley AM,King A,Knights AJ,Lad H,Laird G,Lawlor S,Leongamornlert DA,Lloyd DM,Loveland J,Lovell J,Lush MJ,Lyne R,Martin S,Mashreghi-Mohammadi M,Matthews L,Matthews NS,McLaren S,Milne S,Mistry S,Moore MJ,Nickerson T,O'Dell CN,Oliver K,Palmeiri A,Palmer SA,Parker A,Patel D,Pearce AV,Peck AI,Pelan S,Phelps K,Phillimore BJ,Plumb R,Rajan J,Raymond C,Rouse G,Saenphimmachak C,Sehra HK,Sheridan E,Shownkeen R,Sims S,Skuce CD,Smith M,Steward C,Subramanian S,Sycamore N,Tracey A,Tromans A,Van Helmond Z,Wall M,Wallis JM,White S,Whitehead SL,Wilkinson JE,Willey DL,Williams H,Wilming L,Wray PW,Wu Z,Coulson A,Vaudin M,Sulston JE,Durbin R,Hubbard T,Wooster R,Dunham I,Carter NP,McVean G,Ross MT,Harrow J,Olson MV,Beck S,Rogers J,Bentley DR,Banerjee R,Bryant SP,Burford DC,Burrill WD,Clegg SM,Dhami P,Dovey O,Faulkner LM,Gribble SM,Langford CF,Pandian RD,Porter KM,Prigmore E

Thu May 18 00:00:00 UTC 2006

Molecular analysis and functional expression of the human type E neuronal Ca2+ channel alpha 1 subunit.

Receptors & channels

Schneider T,Wei X,Olcese R,Costantin JL,Neely A,Palade P,Perez-Reyes E,Qin N,Zhou J,Crawford GD

Thu May 25 00:00:00 UTC 1995

Structure and functional characterization of neuronal alpha 1E calcium channel subtypes.

The Journal of biological chemistry

Williams ME,Marubio LM,Deal CR,Hans M,Brust PF,Philipson LH,Miller RJ,Johnson EC,Harpold MM,Ellis SB

Fri Sep 02 00:00:00 UTC 1994

生物信息学

蛋白别名: BII; Brain calcium channel II; Calcium channel, L type, alpha-1 polypeptide, isoform 6; calcium channel, R type, alpha-1 polypeptide, isoform 6; calcium channel, voltage-dependent, L type, alpha 1E subunit; RBE-II; RBE2; voltage gated calcium channel alpha1E subunit; voltage-dependent calcium channel alpha 1E subunit; voltage-dependent calcium channel alpha1-E subunit; Voltage-dependent R-type calcium channel subunit alpha-1E; voltage-gated calcium channel alpha subunit Cav2.3; Voltage-gated calcium channel subunit alpha Cav2.3

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基因别名: A430040I15; alpha1E; BII; CACH6; CACHA1E; CACNA1E; CACNL1A6; Cav2.3; Cchra1; gm139

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UniProt ID: (Human) Q15878

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Entrez Gene ID: (Human) 777, (Rat) 54234, (Mouse) 12290

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功能