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Alomone Labs, LTD
CACNA2D1 (CaV alpha 2 delta 1) (extracellular) Polyclonal Antibody
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CACNA2D1 (CaV alpha 2 delta 1) (extracellular) Antibody (ACC-015-200UL) in ICC/IF
Expression of CaV alpha 2 delta 1 in rat PC12 cells - Cell surface detection of CaV alpha 2 delta 1 in intact living rat Pheochromocytoma (PC12) cells. A. Extracellular staining of cells using Anti-CACNA2D1 (CaV alpha 2 delta 1) (extracellular) Antibody (#ACC-015), (1:50), (red). B. Merge of A with the live view of the cell.
产品信息
ACC-015-200UL
产品规格
种属反应
Human,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
EPFPSAVTIKSWVDK(C), corresponding to amino acid residues 27-41 of rabbit CaV alpha 2 delta 1precursor, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.65 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Calcium channel subunit alpha 2 delta (dihydropyridine - sensitive L-type); calcium channel, L type, alpha 2 polypeptide; calcium channel, voltage-dependent, alpha 2/delta subunit 1; DHP; dihydropryridine-sensitive calcium channel alpha-2 subunit; dihydropyridine-sensitive L-type, calcium channel alpha-2/delta subunit; H_DJ0560O14.1; Voltage-dependent calcium channel subunit alpha-2/delta-1; Voltage-gated calcium channel subunit alpha-2/delta-1; WUGSC:H_DJ0560O14.1
基因别名: CACNA2; CACNA2D1; CACNL2A; CCHL2A; CCHLA2; DHSCCA; LINC01112; lncRNA-N3; MHS3
UniProt ID: (Rabbit) P13806, (Human) P54289
Entrez Gene ID: (Rabbit) 100009105, (Human) 781, (Rat) 25399
calcium ion transport
regulation of calcium ion transport
regulation of ventricular cardiac muscle cell membrane repolarization
calcium ion transport into cytosol
cardiac conduction
calcium ion transmembrane transport via high voltage-gated calcium channel
cardiac muscle cell action potential involved in contraction
membrane depolarization during cardiac muscle cell action potential
regulation of heart rate by cardiac conduction
regulation of membrane repolarization during action potential
positive regulation of high voltage-gated calcium channel activity
regulation of ion transmembrane transport
calcium ion transmembrane transport
