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产品信息
H00000783-M05
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
6C4
抗原
CACNB2 (NP_963890, 213 a.a. approximately 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: PSSRKSTPPS SAIDIDATGL DAEENDIPAN HRSPKPSANS VTSPHSKEKR MPFFKKTEHT PPYDVVPSMR PVVLVGPSLK GYEVTDMMQ
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAB1; CAB2; CACNLB1; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CCHLB1; Lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; Voltage-dependent L-type calcium channel subunit beta-2; voltage-gated calcium channel beta2 subunit transcript variant X13
基因别名: AW060387; CAB2; CACNB2; CACNLB2; CAVB2; Cavbeta2; Cchb2; MYSB
UniProt ID: (Human) Q08289, (Mouse) Q8CC27
Entrez Gene ID: (Human) 783, (Mouse) 12296
voltage-gated calcium channel activity
calcium channel regulator activity
calcium channel activity
protein binding
high voltage-gated calcium channel activity
protein kinase binding
protein domain specific binding
actin filament binding
phosphoprotein binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated ion channel activity
voltage-gated ion channel
chemical synaptic transmission
neuromuscular junction development
visual perception
positive regulation of calcium ion transport
cardiac conduction
calcium ion import
calcium ion transmembrane transport
membrane depolarization during AV node cell action potential
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
membrane depolarization during atrial cardiac muscle cell action potential
regulation of voltage-gated calcium channel activity
positive regulation of high voltage-gated calcium channel activity
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
transport
ion transport
calcium ion transport
regulation of ion transmembrane transport
