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产品信息
PA5-33382
产品规格
种属反应
Bovine,
Dog,
Horse,
Goat,
Hamster,
Human,
Non-human primate,
Pig,
Rabbit,
Rat,
Xenopus
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CALCRL.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2550763
靶标信息
CRLR is a receptor for calcitonin gene-related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B-cell/lung/testis, bome marrow, embryo, lung and synovium libraries.
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生物信息学
蛋白别名: Calcitonin gene-related peptide type 1 receptor; calcitonin gene-related peptide type 1 receptor-like; calcitonin receptor-like; Calcitonin receptor-like receptor; calcitonin-like peptide type 1 receptor; CGRP receptor; CGRP type 1 receptor; Cgrp1 receptor; G protein-coupled receptor
基因别名: CALCRL; CGRPR; CLR; CRLR; RATCRLR; RNCLR
UniProt ID: (Bovine) A6QP74, (Human) Q16602, (Pig) Q8WN93, (Rat) Q63118
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
receptor internalization
angiogenesis
cAMP biosynthetic process
calcium ion transport
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
heart development
protein transport
positive regulation of cAMP biosynthetic process
negative regulation of smooth muscle contraction
positive regulation of smooth muscle cell proliferation
negative regulation of inflammatory response
cellular response to sucrose stimulus
calcitonin gene-related peptide receptor signaling pathway
adrenomedullin receptor signaling pathway
positive regulation of cell proliferation
