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Immunogen sequence: MVKLGCSFSG KPGKDPGDQD GAAMDSVPLI SPLDISQLQP PLPDQVVIKT QTEYQLSSPD QQNFPDLEGQ RLNCSHPEEG RRLPTARMI
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.
Calcyon is a single transmembrane protein that interacts with D1 dopamine receptors. Dopamine is a neurotransmitter that regulates synaptic transmission involved in learning and memory. D1 receptors, the most abundant dopamine receptor in the central nervous system, appear to modulate the activity of D2 dopamine receptors, mediate various behavioural responses, and regulate neuron growth and differentiation. Calcyon is present in neuronal cell bodies and processes of the cortex and hippocampus, and it is especially abundant in pyramidal neurons. Interaction of Calcyon with D1 receptors results in a release of intracellular calcium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: calcyon D1 dopamine receptor-interacting protein (CALCYON); calcyon neuron-specific vesicular protein; calcyon protein; D1 dopamine receptor-interacting protein; dopamine receptor D1 interacting protein; Neuron-specific vesicular protein calcyon
基因别名: CALY; DRD1IP; NSG3
UniProt ID: (Human) Q9NYX4
Entrez Gene ID: (Human) 50632