Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-116776
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 350-650 of human CAMSAP1 (NP_0562623)
偶联物
形式
Liquid
浓度
2.83 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901407
产品详细信息
Positive Samples: HeLa
Immunogen sequence: KTVLHQKSSR PPVPISNATK RSFLGSPAAG TLAELQPPVQ LPAEGCHRHY LHPEEPEYLG KGTAAFSPSH PLLPLRQKQQ KSIQGEDIPD QRHRSNSLTR VDGQPRGAAI AWPEKKTRPA SQPTPFALHH AASCEVDPSS GDSISLARSI SKDSLASNIV NLTPQNQPHP TATKSHGKSL LSNVSIEDEE EELVAIVRAD VVPQQADPEF PRASPRALGL TANARSPQGQ LDTSESKPDS FFLEPLMPAV LKPAKEKQVI TKEDERGEGR PRSIVSRRPS EGPQPLVRRK MTGSRDLNRT F
靶标信息
Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:19508979, PubMed:21834987, PubMed:24486153, PubMed:24706919, PubMed:24117850). Specifically recognizes growing microtubule minus-ends and stabilizes microtubules (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation (PubMed:24486153, PubMed:24706919). Through interaction with spectrin may regulate neurite outgrowth (PubMed:24117850). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Calmodulin-regulated spectrin-associated protein 1; DKFZp434F195; FLJ31228
基因别名: 9530003A05Rik; C77823; CAMSAP1; PRO2405
UniProt ID: (Human) Q5T5Y3, (Mouse) A2AHC3
Entrez Gene ID: (Human) 157922, (Mouse) 227634
